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Index > Protein center > Piezo1(Gene name) > Rat
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  • Piezo1 (Gene name),
  • Piezo-type mechanosensitive ion channel component 1 (Protein name ),  PIEZ1_RAT from NCBI database.
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  • Gene name:
    Piezo1(Fam38a);
    Protein name:
    Piezo-type mechanosensitive ion channel component 1;
    Alternative:
    Protein FAM38A;Membrane protein induced by beta-amyloid treatment(Mib);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Component of mechanosensitive channel required for the mechanosensitive currents. Plays a key role in epithelial cell adhesion by maintaining integrin activation through R-Ras recruitment to the ER, most probably in its activated state, and subsequent stimulation of calpain signaling.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein Endoplasmic reticulum-Golgi intermediate compartment membrane Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    2535
    Sequence:
    50:
    MEPHVLGAGL | YWLLLPCTLL | AASLLRFNAL | SLVYLLFLLL | LPWLPGPSRH | 
    100:
    SIPGHTGRLL | RALLCLSLLF | LVAHVAFQIC | LHTMPRLNQL | LGQNCNLWAN | 
    150:
    VSQHIGVTRL | DLKDIFNTTR | LVAPDLGVLV | ASSLCLGLCG | RLTRKARQSQ | 
    200:
    RTQELEEDDI | DAAPAAGLQG | APTLATKRRL | WLAPRFRITA | HWLLVTSGRM | 
    250:
    LVIVLLALAG | IAHPSAFSSV | YLMVFLAICT | WWSCHFPLSS | LGFNTLCVMV | 
    300:
    SCFGAGHLVC | LYCYQTPFVQ | SVLLPGSLWA | RLFGLKNFVD | IPNCSSPNVL | 
    350:
    VLNTKHAWPI | YVSPGILLLL | YYTATSLLKL | RKGRFSELRK | EIPREDEEHE | 
    400:
    LELDQLEPEP | QARGTTQGAT | PTTTGPDIDN | CTVHVLTSQS | PVRQRPVRPR | 
    450:
    LAELKEMSPL | HGLGHLILDQ | SYVCALIAMM | VWSIMYHSWL | TFVLLLWACL | 
    500:
    IWTVRSRHQL | AMLCSPCILL | YGLTLCCLRY | VWAMELPELP | TTLGPVSLHQ | 
    550:
    LGLEHTRYPC | LDLGAMLLYL | LTFWLLLRQF | VKEKLLKKRK | APSTLLEVTV | 
    600:
    SDTEPTQTQT | LLRSLGELVT | GIYVKYWIYV | CAGMFIVVSF | AGRLVVYKIV | 
    650:
    YMFLFLLCLT | LFQVYYTLWR | KLLRVFWWLV | VAYTMLVLIA | VYTFQFQDFP | 
    700:
    TYWRNLTGFT | DEQLGDLGLE | QFSVSELFSS | ILIPGFFLLA | CILQLHYFHR | 
    750:
    PFMQLTDLEH | VPPPGTRRLR | WAHRQDTVSE | APLLQHQEEE | EVFRDDGQSM | 
    800:
    DGPHQTTQVP | EGTASKWGLV | ADRLLDLASS | FSAVLTRIQV | FVRCLLELHV | 
    850:
    FKLVALYTVW | VALKEVSVMN | LLLVVLWAFA | LPYPRFRPMA | SCLSTVWTCI | 
    900:
    IIVCKMLYQL | KIVNPHEYSS | NCTEPFPNNT | NLQPLEISQS | LLYRGPVDPA | 
    950:
    NWFGVRKGYP | NLGYIQNHLQ | ILLLLVFEAV | VYRRQEHYRR | QHQQAPLPAQ | 
    1000:
    ALCADGTRQR | LDQDLLSCLK | YFINFFFYKF | GLEICFLMAV | NVIGQRMNFM | 
    1050:
    VILHGCWLVA | ILTRRRREAI | ARLWPNYCLF | LTLFLLYQYL | LCLGMPPALC | 
    1100:
    IDYPWRWSQA | IPMNSALIKW | LYLPDFFRAP | NSTNLISDFL | LLLCASQQWQ | 
    1150:
    VFSAEQTEEW | QRMAGVNTDH | LEPLRGEPNP | IPNFIHCRSY | LDMLKVAVFR | 
    1200:
    YLFWLVLVVV | FVTGATRISI | FGLGYLLACF | YLLLFGTTLL | QKDTRAQLVL | 
    1250:
    WDCLILYNVT | VIISKNMLSL | LSCVFVEQMQ | SNFCWVIQLF | SLVCTVKGYY | 
    1300:
    DPKEMKTRDR | DCLLPVEEAG | IIWDSICFFF | LLLQRRVFLS | HYFLHVSADL | 
    1350:
    KATALQASRG | FALYNAANIK | NINFHRQTEE | RSLAQLKRQM | KRIRAKQEKY | 
    1400:
    RQSQASRGQL | QSTDPQEPGP | DSPGGSSPPR | TQWWRPWQDH | ATVIHSGDYF | 
    1450:
    LFESDSEEEE | EALPEDPRPA | AQSAFQMAYQ | AWVTNAQTVL | RQRREQARRD | 
    1500:
    RAEQLASGGD | LSPEVELVDV | PENEMAGHSH | VMQRVLSTMQ | FLWVLGQATV | 
    1550:
    DGLTRWLRTF | TKDHRTMSDV | LCAERYLLTQ | ELLRGGEVHR | GVLDQLYVSE | 
    1600:
    DEIALSGPVE | NRDGPSTASS | GLGAEEPLSS | MTDDTGSPLS | TGYNTRSGSE | 
    1650:
    EIITDTGGLQ | AGTSLHGSQE | LLANARTRMR | TASELLLDRR | LRIPELEEAE | 
    1700:
    QFEAQQGRTL | RLLRAMYQCV | AAHSELLCYF | IIILNHMVTA | SAASLVLPVL | 
    1750:
    VFLWAMLTIP | RPSKRFWMTA | IVFTEVMVVT | KYLFQFGFFP | WNSYIVLRRY | 
    1800:
    ENKPYFPPRI | LGLEKTDSYI | KYDLVQLMAL | FFHRSQLLCY | GLWDHEEDGV | 
    1850:
    PKDHCRSSEK | DQEAEEESEA | KLESQPETGT | GHPEEPVLTG | TPKDHIQGKG | 
    1900:
    SVRSKDEIQD | PPEDLKPQHR | RHISIRFRRR | KETQGPKGAA | VVEAEHEEGE | 
    1950:
    EGREAAGRKR | LRRPREGLKI | REKMKAAGRR | LQSFCLSLAQ | SFYQPLRRFF | 
    2000:
    HDILHTKYRA | ATDVYALMFL | ADIVDIVVII | FGFWAFGKHS | AATDIASSLS | 
    2050:
    DDQVPQAFLF | MLLVQFGTMV | IDRALYLRKT | VLGNLAFQVV | LVVAIHLWMF | 
    2100:
    FILPAVTERM | FRQNAVAQLW | YFVKCIYFAL | SAYQIRCGYP | TRILGNFLTK | 
    2150:
    KYNHLNLFLF | QGFRLVPFLV | ELRAVMDWVW | TDTTLSLSNW | MCVEDIYANI | 
    2200:
    FIIKCSRETE | KKYPQPKGQK | KKKIVKYGMG | GLIILFLIAI | IWFPLLFMSL | 
    2250:
    IRSVVGVVNQ | PIDVTVTLKL | GGYEPLFTMS | AQQPSIVPFT | PEDYEELSQQ | 
    2300:
    FDPYPLAMQF | ISQYSPEDIV | TAQIEGSSGA | LWRISPPSRA | QMKHELYNGT | 
    2350:
    ADITLRFTWN | FQRDLAKGGS | VEYTNEKHTL | ELAPNSTARR | QLAQLLEGRP | 
    2400:
    DQSVVIPHLF | PKYIRAPNGP | EANPVKQLQP | DEEEDYLGVR | IQLRREQVGT | 
    2450:
    GTSGEQAGTK | ASDFLEWWVI | ELQDCQAECN | LLPMVIFSDK | VSPPSLGFLA | 
    2500:
    GYGIVGLYVS | IVLVVGKFVR | GFFSDISHSI | MFEELPCVDR | ILKLCQDIFL | 
    2535:
    VRETRELELE | EELYAKLIFL | YRSPETMIKW | TREKE
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Piezo-type mechanosensitive ion channel component 1
    Cat.:
    E3227h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Piezo-type mechanosensitive ion channel component 1
    Cat.:
    E3227r
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Piezo-type mechanosensitive ion channel component 1
    Cat.:
    E3227m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Piezo-type mechanosensitive ion channel component 1
    Cat.:
    U3227m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Piezo-type mechanosensitive ion channel component 1
    Cat.:
    U3227h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Piezo-type mechanosensitive ion channel component 1
    Cat.:
    U3227r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Piezo-type mechanosensitive ion channel component 1
    Cat.:
    P3227Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Piezo-type mechanosensitive ion channel component 1
    Cat.:
    P3227Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Piezo-type mechanosensitive ion channel component 1
    Cat.:
    P3227Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Piezo-type mechanosensitive ion channel component 1
    Monoclonal Antibody for Rat Piezo-type mechanosensitive ion channel component 1
    Monoclonal Antibody for Rat Piezo-type mechanosensitive ion channel component 1
    Protein for Rat Piezo-type mechanosensitive ion channel component 1
    Protein for Rat Piezo-type mechanosensitive ion channel component 1
    Protein for Rat Piezo-type mechanosensitive ion channel component 1

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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "A novel membrane protein, encoded by the gene covering KIAA0233, is transcriptionally induced in senile plaque-associated astrocytes."
      Satoh K. , Hata M. , Takahara S. , Tsuzaki H. , Yokota H. , Akatsu H. , Yamamoto T. , Kosaka K. , Yamada T.
      Brain Res.1108:19-27(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 430-2535;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION
      strain: Wistar.
      tissue: Astrocyte.
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